808118-40-3 Roxadustat

Airíonna

Dealramh solad as-bán nó bán
Leáphointe: {199-215 Céim
Fiuchphointe: 684.3 ± 55. {0 Céim (tuartha)
Dlús 1.389
Teocht stórála. Céim -20
Intuaslagthacht intuaslagtha i DMSO (suas le 25 mg/ml ar a laghad).
PKA2.46 ± 0. 10
 

Iarratas:

Is éard atá i Roxadustat ná coscaire hydroxylase propyl hypoxia béil (HIF-PHI) a fuair a chéad fhaomhadh domhanda sa tSín i mí na Nollag 2018 chun cóireáil a dhéanamh ar anemia de bharr CKD in othair atá ag brath ar scagdhealú.

 

Comhchiallaigh:

(Rxadustat

808118-40-3

Fg -4592

FG4592

Roxadustat (fg -4592)

N-[{4- hydroxy {-1- meitil {-7- fenoxy {-3- isoquinolinyl) glicín carbóinigh]

Asp 1517

{2- [(4- hydroxy -1- meitil {-7- phenoxyisoquinoline -3- carbonyl) Aigéad aimín]

(de chuid na Rxadustatum

Asp -1517

Glycine, n-[(4- hiodrocsa -1- meitil -7- fenoxy -3- isoquinolinyl)-

(.

N-[{4- hydroxy {-1- methyl {-7- phenoxyisoquinolin -3- yl) glicín carbón

.

2- (4- hydroxy -1- meitil -7- phenoxyisoquinoline -3- carboxamido) aigéad aicéiteach)

Evrenzo

{2- [[4- hydroxy -1- meitil -7- (fenoxy) isoquinoline -3- carbonyl] aigéad aicéiteach aimín]

Glycine, n-({4- hiodrocsa -1- meitil -7- fenoxy -3- isoquinolinyl) Carbonyl)-

 

Clibeanna Te: {808118-40-3 Roxadustat, an tSín 808118-40-3 monaróirí, soláthróirí